BRD-K53561341_KIN001-220_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

92 genes differentially expressed following the BRD-K53561341_KIN001-220_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CPM carboxypeptidase M
CTSZ cathepsin Z
CXCL13 chemokine (C-X-C motif) ligand 13
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4 DNA-damage-inducible transcript 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPAS1 endothelial PAS domain protein 1
FAM69A family with sequence similarity 69, member A
FAS Fas cell surface death receptor
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GAGE3 G antigen 3
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
KCTD5 potassium channel tetramerization domain containing 5
MBNL2 muscleblind-like splicing regulator 2
MVP major vault protein
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PHF20 PHD finger protein 20
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRKCZ protein kinase C, zeta
REG1A regenerating islet-derived 1 alpha
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SERTAD2 SERTA domain containing 2
SOX9 SRY (sex determining region Y)-box 9
STXBP1 syntaxin binding protein 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TP53I3 tumor protein p53 inducible protein 3
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
UBB ubiquitin B
XIST X inactive specific transcript (non-protein coding)
YBX3 Y box binding protein 3
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB18 zinc finger and BTB domain containing 18
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCHE butyrylcholinesterase
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C3 complement component 3
CCNF cyclin F
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK1 cyclin-dependent kinase 1
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHEK2 checkpoint kinase 2
COPS7A COP9 signalosome subunit 7A
FAM129A family with sequence similarity 129, member A
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FMOD fibromodulin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPC3 glypican 3
HIST1H4C histone cluster 1, H4c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LXN latexin
NREP neuronal regeneration related protein
PAH phenylalanine hydroxylase
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRL platelet-derived growth factor receptor-like
PITX1 paired-like homeodomain 1
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PON3 paraoxonase 3
POSTN periostin, osteoblast specific factor
RFC5 replication factor C (activator 1) 5, 36.5kDa
S100A6 S100 calcium binding protein A6
SPINK1 serine peptidase inhibitor, Kazal type 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28