BRD-K53461563_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K53461563_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ACOT7 acyl-CoA thioesterase 7
AKR1C3 aldo-keto reductase family 1, member C3
ANXA4 annexin A4
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CLCA2 chloride channel accessory 2
CRABP1 cellular retinoic acid binding protein 1
DDIT4 DNA-damage-inducible transcript 4
EMP3 epithelial membrane protein 3
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXG1 forkhead box G1
FRZB frizzled-related protein
G6PD glucose-6-phosphate dehydrogenase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
H1FX H1 histone family, member X
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HILPDA hypoxia inducible lipid droplet-associated
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KLHL7 kelch-like family member 7
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
MXRA7 matrix-remodelling associated 7
NES nestin
NOTCH1 notch 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG10 paternally expressed 10
PER1 period circadian clock 1
PLAGL1 pleiomorphic adenoma gene-like 1
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
QPCT glutaminyl-peptide cyclotransferase
RGS1 regulator of G-protein signaling 1
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC1 syndecan 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TAPBP TAP binding protein (tapasin)
TMEM45A transmembrane protein 45A
TUSC3 tumor suppressor candidate 3
VCAM1 vascular cell adhesion molecule 1
VIM vimentin

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AGR2 anterior gradient 2
ANKRD10 ankyrin repeat domain 10
ATF5 activating transcription factor 5
C14ORF2 chromosome 14 open reading frame 2
CCNE2 cyclin E2
CCNF cyclin F
CHL1 cell adhesion molecule L1-like
COL15A1 collagen, type XV, alpha 1
DCN decorin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
F5 coagulation factor V (proaccelerin, labile factor)
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLUL glutamate-ammonia ligase
HOXC6 homeobox C6
HSPA2 heat shock 70kDa protein 2
HSPA8 heat shock 70kDa protein 8
KEAP1 kelch-like ECH-associated protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MTUS1 microtubule associated tumor suppressor 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
RPL37A ribosomal protein L37a
RSL1D1 ribosomal L1 domain containing 1
SEPP1 selenoprotein P, plasma, 1
SFPQ splicing factor proline/glutamine-rich
SMAD1 SMAD family member 1
TESC tescalcin
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM87A transmembrane protein 87A
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN1 tetraspanin 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WT1 Wilms tumor 1