BRD-K53417444_OTSSP167_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

206 genes differentially expressed following the BRD-K53417444_OTSSP167_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANPEP alanyl (membrane) aminopeptidase
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ASRGL1 asparaginase like 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BAG1 BCL2-associated athanogene
CAV2 caveolin 2
CCL5 chemokine (C-C motif) ligand 5
CCND2 cyclin D2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CPD carboxypeptidase D
CPM carboxypeptidase M
CTGF connective tissue growth factor
CXADR coxsackie virus and adenovirus receptor
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DBN1 drebrin 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLC1 DLC1 Rho GTPase activating protein
DUSP1 dual specificity phosphatase 1
EPAS1 endothelial PAS domain protein 1
EXPH5 exophilin 5
F2R coagulation factor II (thrombin) receptor
FAM3C family with sequence similarity 3, member C
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPNMB glycoprotein (transmembrane) nmb
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL13RA1 interleukin 13 receptor, alpha 1
ISG15 ISG15 ubiquitin-like modifier
ISYNA1 inositol-3-phosphate synthase 1
LAMP3 lysosomal-associated membrane protein 3
LHX2 LIM homeobox 2
LOX lysyl oxidase
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MEF2C myocyte enhancer factor 2C
MFAP3L microfibrillar-associated protein 3-like
MGLL monoglyceride lipase
MSN moesin
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
MX1 MX dynamin-like GTPase 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRGN neurogranin (protein kinase C substrate, RC3)
OLFM4 olfactomedin 4
OPHN1 oligophrenin 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZD2 PDZ domain containing 2
PDZK1IP1 PDZK1 interacting protein 1
PLIN1 perilipin 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
PSPH phosphoserine phosphatase
PTCH1 patched 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB3B RAB3B, member RAS oncogene family
RGS4 regulator of G-protein signaling 4
RHOBTB3 Rho-related BTB domain containing 3
RSAD2 radical S-adenosyl methionine domain containing 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SCARB2 scavenger receptor class B, member 2
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPT6 septin 6
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPRY4 sprouty homolog 4 (Drosophila)
SRPR signal recognition particle receptor (docking protein)
STC1 stanniocalcin 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TMSB15A thymosin beta 15a
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNL4B thioredoxin-like 4B
VLDLR very low density lipoprotein receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
VWA5A von Willebrand factor A domain containing 5A
WSB1 WD repeat and SOCS box containing 1
XAF1 XIAP associated factor 1
XIST X inactive specific transcript (non-protein coding)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
ATF1 activating transcription factor 1
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BCL2A1 BCL2-related protein A1
C2CD5 C2 calcium-dependent domain containing 5
CA1 carbonic anhydrase I
CALML3 calmodulin-like 3
CCNA2 cyclin A2
CD24 CD24 molecule
CD58 CD58 molecule
CDC20 cell division cycle 20
CDK1 cyclin-dependent kinase 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHPT1 choline phosphotransferase 1
CSTA cystatin A (stefin A)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCK deoxycytidine kinase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5 eukaryotic translation initiation factor 5
FERMT1 fermitin family member 1
FOXJ3 forkhead box J3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA3 GATA binding protein 3
HBD hemoglobin, delta
HEATR1 HEAT repeat containing 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
JCHAIN joining chain of multimeric IgA and IgM
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KYNU kynureninase
LMBRD1 LMBR1 domain containing 1
LY6D lymphocyte antigen 6 complex, locus D
MAL mal, T-cell differentiation protein
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MREG melanoregulin
NCOA3 nuclear receptor coactivator 3
NKX3-1 NK3 homeobox 1
NOL11 nucleolar protein 11
NUP62 nucleoporin 62kDa
OPN3 opsin 3
PARP2 poly (ADP-ribose) polymerase 2
PCNA proliferating cell nuclear antigen
PFKP phosphofructokinase, platelet
PHF20 PHD finger protein 20
PLN phospholamban
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PUF60 poly-U binding splicing factor 60KDa
RAE1 ribonucleic acid export 1
RNMT RNA (guanine-7-) methyltransferase
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
STIP1 stress-induced phosphoprotein 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACSTD2 tumor-associated calcium signal transducer 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBP TATA box binding protein
TFB2M transcription factor B2, mitochondrial
TFF1 trefoil factor 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM9SF3 transmembrane 9 superfamily member 3
TMEM176B transmembrane protein 176B
TOX3 TOX high mobility group box family member 3
TSKU tsukushi, small leucine rich proteoglycan
UBE2C ubiquitin-conjugating enzyme E2C
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCAM1 vascular cell adhesion molecule 1
VGLL4 vestigial-like family member 4
XBP1 X-box binding protein 1