BRD-K53414658_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K53414658_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTGF connective tissue growth factor
CTSA cathepsin A
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
G0S2 G0/G1 switch 2
GPX3 glutathione peroxidase 3
IER3 immediate early response 3
KRT15 keratin 15, type I
PDLIM2 PDZ and LIM domain 2 (mystique)
PLAU plasminogen activator, urokinase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP1 secreted frizzled-related protein 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORBS3 sorbin and SH3 domain containing 3
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ATF5 activating transcription factor 5
FGG fibrinogen gamma chain
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB8 heat shock 22kDa protein 8
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
RHOBTB3 Rho-related BTB domain containing 3