BRD-K52911425_GDC-0941_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K52911425_GDC-0941_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK5 adenylate kinase 5
AZU1 azurocidin 1
BASP1 brain abundant, membrane attached signal protein 1
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLC Charcot-Leyden crystal galectin
CLU clusterin
CPA3 carboxypeptidase A3 (mast cell)
CRISP3 cysteine-rich secretory protein 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DLK1 delta-like 1 homolog (Drosophila)
ELANE elastase, neutrophil expressed
FAM46A family with sequence similarity 46, member A
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HNMT histamine N-methyltransferase
HTRA1 HtrA serine peptidase 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KRT19 keratin 19, type I
LAMP2 lysosomal-associated membrane protein 2
LOXL1 lysyl oxidase-like 1
LTF lactotransferrin
MPO myeloperoxidase
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PRDX2 peroxiredoxin 2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SNAP25 synaptosomal-associated protein, 25kDa
SYNJ2 synaptojanin 2
TIMP1 TIMP metallopeptidase inhibitor 1
TMC5 transmembrane channel-like 5
TST thiosulfate sulfurtransferase (rhodanese)
TXNIP thioredoxin interacting protein
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CEP55 centrosomal protein 55kDa
CKS2 CDC28 protein kinase regulatory subunit 2
CYCS cytochrome c, somatic
DHRS7 dehydrogenase/reductase (SDR family) member 7
EIF5 eukaryotic translation initiation factor 5
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GCH1 GTP cyclohydrolase 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIF20A kinesin family member 20A
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPK6 mitogen-activated protein kinase 6
MELK maternal embryonic leucine zipper kinase
MKI67 marker of proliferation Ki-67
MOXD1 monooxygenase, DBH-like 1
NEK2 NIMA-related kinase 2
PBK PDZ binding kinase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
PRC1 protein regulator of cytokinesis 1
PTTG1 pituitary tumor-transforming 1
TDO2 tryptophan 2,3-dioxygenase
TPX2 TPX2, microtubule-associated
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S