BRD-K52911425_GDC-0941_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K52911425_GDC-0941_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARMCX1 armadillo repeat containing, X-linked 1
CCL20 chemokine (C-C motif) ligand 20
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
FAM129A family with sequence similarity 129, member A
FAM134B family with sequence similarity 134, member B
FBN2 fibrillin 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXC6 homeobox C6
ITM2A integral membrane protein 2A
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LCN2 lipocalin 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
METTL7A methyltransferase like 7A
MTCL1 microtubule crosslinking factor 1
MYBPC1 myosin binding protein C, slow type
OSBPL1A oxysterol binding protein-like 1A
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCOLCE procollagen C-endopeptidase enhancer
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLA2G16 phospholipase A2, group XVI
PROM1 prominin 1
PTN pleiotrophin
SFRP1 secreted frizzled-related protein 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SOD2 superoxide dismutase 2, mitochondrial
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TTN titin
USP6NL USP6 N-terminal like
WDTC1 WD and tetratricopeptide repeats 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
C2CD2 C2 calcium-dependent domain containing 2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DUSP6 dual specificity phosphatase 6
F13A1 coagulation factor XIII, A1 polypeptide
FAM107A family with sequence similarity 107, member A
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBB hemoglobin, beta
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KRT7 keratin 7, type II
LMO3 LIM domain only 3 (rhombotin-like 2)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100P S100 calcium binding protein P
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TKT transketolase
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZYX zyxin