BRD-K52911425_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K52911425_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK3 aarF domain containing kinase 3
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARHGAP32 Rho GTPase activating protein 32
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC28A coiled-coil domain containing 28A
CCNG2 cyclin G2
CEP57 centrosomal protein 57kDa
CFB complement factor B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
HBP1 HMG-box transcription factor 1
INSIG1 insulin induced gene 1
KDM3A lysine (K)-specific demethylase 3A
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBR1 neighbor of BRCA1 gene 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PNRC1 proline-rich nuclear receptor coactivator 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC38A2 solute carrier family 38, member 2
TFF3 trefoil factor 3 (intestinal)
TKTL1 transketolase-like 1
TMEM135 transmembrane protein 135
TPP1 tripeptidyl peptidase I
TXNIP thioredoxin interacting protein
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCND3 cyclin D3
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDR2L cerebellar degeneration-related protein 2-like
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CTPS1 CTP synthase 1
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GAS2L1 growth arrest-specific 2 like 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
HBEGF heparin-binding EGF-like growth factor
HN1 hematological and neurological expressed 1
HSPB8 heat shock 22kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
JMJD6 jumonji domain containing 6
LRRC59 leucine rich repeat containing 59
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NOP16 NOP16 nucleolar protein
PFKP phosphofructokinase, platelet
PHLDA2 pleckstrin homology-like domain, family A, member 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRSF2 serine/arginine-rich splicing factor 2
TUBB4B tubulin, beta 4B class IVb
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)