BRD-K52512893_SC 19220_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K52512893_SC 19220_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BASP1 brain abundant, membrane attached signal protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYNLT3 dynein, light chain, Tctex-type 3
GNAS GNAS complex locus
GSAP gamma-secretase activating protein
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP3 insulin-like growth factor binding protein 3
MBOAT7 membrane bound O-acyltransferase domain containing 7
PLAC8 placenta-specific 8
PRAME preferentially expressed antigen in melanoma
RGS1 regulator of G-protein signaling 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
CADM1 cell adhesion molecule 1
CRABP1 cellular retinoic acid binding protein 1
CRIP2 cysteine-rich protein 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
FZD10 frizzled class receptor 10
GATA3 GATA binding protein 3
KRT19 keratin 19, type I
SMAD1 SMAD family member 1
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TPBG trophoblast glycoprotein
TUBB2A tubulin, beta 2A class IIa
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1