BRD-K52075715_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-K52075715_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXB2 homeobox B2
HSPA1A heat shock 70kDa protein 1A
PENK proenkephalin
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AKAP12 A kinase (PRKA) anchor protein 12
CHRDL1 chordin-like 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EDNRA endothelin receptor type A
FHL1 four and a half LIM domains 1
IGFBP7 insulin-like growth factor binding protein 7
MYH11 myosin, heavy chain 11, smooth muscle
SYT1 synaptotagmin I
UBE2J1 ubiquitin-conjugating enzyme E2, J1