BRD-K51998148_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K51998148_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLU clusterin
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GLRX glutaredoxin (thioltransferase)
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSN moesin
NDRG1 N-myc downstream regulated 1
NELL2 NEL-like 2 (chicken)
S100P S100 calcium binding protein P
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
TM4SF1 transmembrane 4 L six family member 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CADPS2 Ca++-dependent secretion activator 2
CREB1 cAMP responsive element binding protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
RND3 Rho family GTPase 3
SS18 synovial sarcoma translocation, chromosome 18
ZNF91 zinc finger protein 91