BRD-K51998148_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

72 genes differentially expressed following the BRD-K51998148_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX1 brain expressed, X-linked 1
BHLHE40 basic helix-loop-helix family, member e40
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLIC4 chloride intracellular channel 4
CTSH cathepsin H
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DAPK1 death-associated protein kinase 1
DCN decorin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FADS1 fatty acid desaturase 1
GNAS GNAS complex locus
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL32 interleukin 32
KRT17 keratin 17, type I
LAT2 linker for activation of T cells family, member 2
MAP7 microtubule-associated protein 7
MN1 meningioma (disrupted in balanced translocation) 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PHACTR2 phosphatase and actin regulator 2
PLCB4 phospholipase C, beta 4
RGS5 regulator of G-protein signaling 5
SPRR1A small proline-rich protein 1A
STK26 serine/threonine protein kinase 26
TCF4 transcription factor 4
TSPAN13 tetraspanin 13
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ARL4A ADP-ribosylation factor-like 4A
CALB1 calbindin 1, 28kDa
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCNE2 cyclin E2
CNN1 calponin 1, basic, smooth muscle
COL1A2 collagen, type I, alpha 2
CRISP3 cysteine-rich secretory protein 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS2 dehydrogenase/reductase (SDR family) member 2
EMP1 epithelial membrane protein 1
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GPM6B glycoprotein M6B
HIST1H2AC histone cluster 1, H2ac
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
LCN2 lipocalin 2
LEPR leptin receptor
LMO4 LIM domain only 4
LPL lipoprotein lipase
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRUNE2 prune homolog 2 (Drosophila)
PTX3 pentraxin 3, long
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SET SET nuclear proto-oncogene
SH3YL1 SH3 and SYLF domain containing 1
SPEN spen family transcriptional repressor
SRPX sushi-repeat containing protein, X-linked
SRSF7 serine/arginine-rich splicing factor 7
VAT1 vesicle amine transport 1