BRD-K51791390_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K51791390_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRABP2 cellular retinoic acid binding protein 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DDIT4 DNA-damage-inducible transcript 4
EIF5A eukaryotic translation initiation factor 5A
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
MT1M metallothionein 1M
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLIN2 perilipin 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
SMAD3 SMAD family member 3
TPD52L1 tumor protein D52-like 1
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ASS1 argininosuccinate synthase 1
CCND1 cyclin D1
COL5A2 collagen, type V, alpha 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GOLGA8A golgin A8 family, member A
GOLM1 golgi membrane protein 1
JADE2 jade family PHD finger 2
KLHL21 kelch-like family member 21
LTF lactotransferrin
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A9 S100 calcium binding protein A9
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4