BRD-K51683034_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K51683034_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CBS cystathionine-beta-synthase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL3A1 collagen, type III, alpha 1
DDIT4 DNA-damage-inducible transcript 4
ENAH enabled homolog (Drosophila)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HIST1H1C histone cluster 1, H1c
HIST2H2BE histone cluster 2, H2be
HMOX1 heme oxygenase 1
IDS iduronate 2-sulfatase
LDOC1 leucine zipper, down-regulated in cancer 1
MMP12 matrix metallopeptidase 12
MYO6 myosin VI
NFE2 nuclear factor, erythroid 2
PHGDH phosphoglycerate dehydrogenase
QPCT glutaminyl-peptide cyclotransferase
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SFTPB surfactant protein B
SQSTM1 sequestosome 1
SST somatostatin
TSKU tsukushi, small leucine rich proteoglycan
WNT5A wingless-type MMTV integration site family, member 5A
ZMAT3 zinc finger, matrin-type 3
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSRP2 cysteine and glycine-rich protein 2
DLD dihydrolipoamide dehydrogenase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
KIF14 kinesin family member 14
MELK maternal embryonic leucine zipper kinase
MSMB microseminoprotein, beta-
MYBPC1 myosin binding protein C, slow type
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPY1R neuropeptide Y receptor Y1
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon