BRD-K51575138_TPCA-1_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K51575138_TPCA-1_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C2CD5 C2 calcium-dependent domain containing 5
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DST dystonin
EGR1 early growth response 1
FAM129A family with sequence similarity 129, member A
FTH1 ferritin, heavy polypeptide 1
FZD7 frizzled class receptor 7
HIST1H2BG histone cluster 1, H2bg
IFI44 interferon-induced protein 44
IRS2 insulin receptor substrate 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KRT15 keratin 15, type I
LY6E lymphocyte antigen 6 complex, locus E
MT1M metallothionein 1M
MT1X metallothionein 1X
NNMT nicotinamide N-methyltransferase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SCGB2A2 secretoglobin, family 2A, member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SPRED2 sprouty-related, EVH1 domain containing 2
STC2 stanniocalcin 2
TSPYL5 TSPY-like 5
TXNIP thioredoxin interacting protein
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALAS2 5'-aminolevulinate synthase 2
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CD47 CD47 molecule
CD69 CD69 molecule
CLCA1 chloride channel accessory 1
DACH1 dachshund family transcription factor 1
DCN decorin
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DSC2 desmocollin 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GOLT1B golgi transport 1B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IGFBP3 insulin-like growth factor binding protein 3
IGHM immunoglobulin heavy constant mu
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAPTM4B lysosomal protein transmembrane 4 beta
LUM lumican
MOXD1 monooxygenase, DBH-like 1
MTUS1 microtubule associated tumor suppressor 1
MUC2 mucin 2, oligomeric mucus/gel-forming
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OLFM4 olfactomedin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PNP purine nucleoside phosphorylase
PON2 paraoxonase 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK1 serine peptidase inhibitor, Kazal type 1
SST somatostatin
STAB1 stabilin 1
TFF1 trefoil factor 1
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3
TRAM1 translocation associated membrane protein 1
VDAC1 voltage-dependent anion channel 1