BRD-K51443908_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K51443908_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
C10ORF10 chromosome 10 open reading frame 10
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
EMP1 epithelial membrane protein 1
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
ISG20 interferon stimulated exonuclease gene 20kDa
MFAP2 microfibrillar-associated protein 2
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEBL nebulette
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PLAU plasminogen activator, urokinase
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCYL3 SCY1-like 3 (S. cerevisiae)
SDC1 syndecan 1
SDC4 syndecan 4
SRRM2 serine/arginine repetitive matrix 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
ATF5 activating transcription factor 5
CDC25A cell division cycle 25A
DEGS1 delta(4)-desaturase, sphingolipid 1
FASTKD5 FAST kinase domains 5
FBXO21 F-box protein 21
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
HBD hemoglobin, delta
HSPA1A heat shock 70kDa protein 1A
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL13RA2 interleukin 13 receptor, alpha 2
IL6ST interleukin 6 signal transducer
KIF14 kinesin family member 14
MTDH metadherin
NCALD neurocalcin delta
NFIB nuclear factor I/B
NOP56 NOP56 ribonucleoprotein
PDGFC platelet derived growth factor C
PDLIM5 PDZ and LIM domain 5
RAD23B RAD23 homolog B (S. cerevisiae)
SFPQ splicing factor proline/glutamine-rich
TCF4 transcription factor 4
TGM2 transglutaminase 2
TSPAN13 tetraspanin 13
UBE2G2 ubiquitin-conjugating enzyme E2G 2
WT1 Wilms tumor 1