BRD-K51443908_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K51443908_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CAST calpastatin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CNPY3 canopy FGF signaling regulator 3
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
EXOSC4 exosome component 4
FBP1 fructose-1,6-bisphosphatase 1
FOLR1 folate receptor 1 (adult)
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GRIA2 glutamate receptor, ionotropic, AMPA 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
INHBA inhibin, beta A
IVNS1ABP influenza virus NS1A binding protein
JCHAIN joining chain of multimeric IgA and IgM
JMJD1C jumonji domain containing 1C
KIAA0226L KIAA0226-like
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NT5E 5'-nucleotidase, ecto (CD73)
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLBD1 phospholipase B domain containing 1
RGS4 regulator of G-protein signaling 4
SEC14L1 SEC14-like 1 (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SRRM2 serine/arginine repetitive matrix 2
TBX2 T-box 2
UGCG UDP-glucose ceramide glucosyltransferase
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BLCAP bladder cancer associated protein
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CBX1 chromobox homolog 1
CCNB1 cyclin B1
CD24 CD24 molecule
CST7 cystatin F (leukocystatin)
CYTL1 cytokine-like 1
DLK1 delta-like 1 homolog (Drosophila)
FASTKD5 FAST kinase domains 5
HOXA10 homeobox A10
JAG1 jagged 1
KLK11 kallikrein-related peptidase 11
MATN2 matrilin 2
MCM3 minichromosome maintenance complex component 3
NRN1 neuritin 1
PFKP phosphofructokinase, platelet
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLK1 polo-like kinase 1
RRM2 ribonucleotide reductase M2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPP1 selenoprotein P, plasma, 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLPI secretory leukocyte peptidase inhibitor
SNX11 sorting nexin 11
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STAR steroidogenic acute regulatory protein
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB2A tubulin, beta 2A class IIa