BRD-K51350053_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K51350053_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AIM1 absent in melanoma 1
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BPGM 2,3-bisphosphoglycerate mutase
BTG2 BTG family, member 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNG2 cyclin G2
CD24 CD24 molecule
CD9 CD9 molecule
CDK19 cyclin-dependent kinase 19
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLDN4 claudin 4
CLU clusterin
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
FAM63A family with sequence similarity 63, member A
FBN2 fibrillin 2
GRN granulin
GSN gelsolin
HCAR3 hydroxycarboxylic acid receptor 3
HEBP1 heme binding protein 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
INSIG1 insulin induced gene 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MAGED2 melanoma antigen family D2
MB myoglobin
MYBPC1 myosin binding protein C, slow type
MYO6 myosin VI
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLIN2 perilipin 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAP1GAP RAP1 GTPase activating protein
RBM47 RNA binding motif protein 47
S100A11 S100 calcium binding protein A11
SAT1 spermidine/spermine N1-acetyltransferase 1
SCPEP1 serine carboxypeptidase 1
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMAD3 SMAD family member 3
SPATA20 spermatogenesis associated 20
STAP2 signal transducing adaptor family member 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TPP1 tripeptidyl peptidase I
TRIM16 tripartite motif containing 16
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AOX1 aldehyde oxidase 1
BTG3 BTG family, member 3
CAST calpastatin
CDC20 cell division cycle 20
CEP55 centrosomal protein 55kDa
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EXOSC2 exosome component 2
FEN1 flap structure-specific endonuclease 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GREB1 growth regulation by estrogen in breast cancer 1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
IGF1 insulin-like growth factor 1 (somatomedin C)
KIF14 kinesin family member 14
MCM10 minichromosome maintenance complex component 10
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
NMU neuromedin U
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NRIP1 nuclear receptor interacting protein 1
ODC1 ornithine decarboxylase 1
OIP5 Opa interacting protein 5
ORC5 origin recognition complex, subunit 5
PAK1IP1 PAK1 interacting protein 1
PLK1 polo-like kinase 1
PPIF peptidylprolyl isomerase F
PRSS23 protease, serine, 23
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RFC3 replication factor C (activator 1) 3, 38kDa
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMC2 structural maintenance of chromosomes 2
TACC3 transforming, acidic coiled-coil containing protein 3
TRA2B transformer 2 beta homolog (Drosophila)
TRIM14 tripartite motif containing 14
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
UBE2S ubiquitin-conjugating enzyme E2S
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta