BRD-K51318897_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K51318897_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BPHL biphenyl hydrolase-like (serine hydrolase)
CALD1 caldesmon 1
CD24 CD24 molecule
CTGF connective tissue growth factor
DCK deoxycytidine kinase
DKK1 dickkopf WNT signaling pathway inhibitor 1
FGFR3 fibroblast growth factor receptor 3
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GPX1 glutathione peroxidase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
PRSS23 protease, serine, 23
RHCG Rh family, C glycoprotein
S100A10 S100 calcium binding protein A10
SFN stratifin
SQLE squalene epoxidase
TPM1 tropomyosin 1 (alpha)
TPM4 tropomyosin 4
TUBB2A tubulin, beta 2A class IIa
UGCG UDP-glucose ceramide glucosyltransferase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BHLHE41 basic helix-loop-helix family, member e41
C14ORF132 chromosome 14 open reading frame 132
C8ORF4 chromosome 8 open reading frame 4
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
EIF5A eukaryotic translation initiation factor 5A
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
IGL immunoglobulin lambda locus
NEFH neurofilament, heavy polypeptide
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RGS2 regulator of G-protein signaling 2
TMSB15A thymosin beta 15a