BRD-K51313569_palbociclib_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the BRD-K51313569_palbociclib_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CD44 CD44 molecule (Indian blood group)
COL4A5 collagen, type IV, alpha 5
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DES desmin
EPN2 epsin 2
FKBP14 FK506 binding protein 14, 22 kDa
HBEGF heparin-binding EGF-like growth factor
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5A lysine (K)-specific demethylase 5A
KRT19 keratin 19, type I
MMP10 matrix metallopeptidase 10
MX1 MX dynamin-like GTPase 1
OAT ornithine aminotransferase
PECR peroxisomal trans-2-enoyl-CoA reductase
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SH3BGRL SH3 domain binding glutamate-rich protein like
TM4SF1 transmembrane 4 L six family member 1
TRPS1 trichorhinophalangeal syndrome I

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CCNE2 cyclin E2
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
IL32 interleukin 32
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NT5DC2 5'-nucleotidase domain containing 2
PARP2 poly (ADP-ribose) polymerase 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A9 S100 calcium binding protein A9
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
STMN2 stathmin 2
TFF1 trefoil factor 1
USP1 ubiquitin specific peptidase 1
WEE1 WEE1 G2 checkpoint kinase
ZBTB20 zinc finger and BTB domain containing 20