BRD-K51276371_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K51276371_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BSG basigin (Ok blood group)
C10ORF10 chromosome 10 open reading frame 10
CD44 CD44 molecule (Indian blood group)
COLEC12 collectin sub-family member 12
COPA coatomer protein complex, subunit alpha
CXADR coxsackie virus and adenovirus receptor
ERBB4 erb-b2 receptor tyrosine kinase 4
F11R F11 receptor
HCAR3 hydroxycarboxylic acid receptor 3
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IGFBP5 insulin-like growth factor binding protein 5
IL13RA1 interleukin 13 receptor, alpha 1
INHBB inhibin, beta B
IQGAP1 IQ motif containing GTPase activating protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEG10 paternally expressed 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RND3 Rho family GTPase 3
SDC2 syndecan 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TWIST1 twist family bHLH transcription factor 1
WLS wntless Wnt ligand secretion mediator
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ADGRG6 adhesion G protein-coupled receptor G6
CKS2 CDC28 protein kinase regulatory subunit 2
CYBA cytochrome b-245, alpha polypeptide
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
FCGBP Fc fragment of IgG binding protein
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX2 glutathione peroxidase 2
HAMP hepcidin antimicrobial peptide
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
KLF2 Kruppel-like factor 2
LDLR low density lipoprotein receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYZ lysozyme
MARCKSL1 MARCKS-like 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFAP3L microfibrillar-associated protein 3-like
NQO1 NAD(P)H dehydrogenase, quinone 1
PHYH phytanoyl-CoA 2-hydroxylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRKCA protein kinase C, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RHOBTB3 Rho-related BTB domain containing 3
RPP25 ribonuclease P/MRP 25kDa subunit
RPS27L ribosomal protein S27-like
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
S100P S100 calcium binding protein P
SCAND1 SCAN domain containing 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)