BRD-K51276371_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K51276371_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
CD9 CD9 molecule
CYR61 cysteine-rich, angiogenic inducer, 61
DKK3 dickkopf WNT signaling pathway inhibitor 3
DST dystonin
DUSP4 dual specificity phosphatase 4
EVL Enah/Vasp-like
FHL2 four and a half LIM domains 2
GPC3 glypican 3
GPM6A glycoprotein M6A
GSTM3 glutathione S-transferase mu 3 (brain)
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
LAPTM4B lysosomal protein transmembrane 4 beta
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRN3 leucine rich repeat neuronal 3
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PERP PERP, TP53 apoptosis effector
PHLDA1 pleckstrin homology-like domain, family A, member 1
RCAN1 regulator of calcineurin 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SLC22A18 solute carrier family 22, member 18
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPRED2 sprouty-related, EVH1 domain containing 2
TFF3 trefoil factor 3 (intestinal)
TPBG trophoblast glycoprotein
TSPAN4 tetraspanin 4
TSTA3 tissue specific transplantation antigen P35B

decreased expression

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF5 activating transcription factor 5
BAMBI BMP and activin membrane-bound inhibitor
C1QB complement component 1, q subcomponent, B chain
CENPA centromere protein A
DNM1L dynamin 1-like
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
H2AFV H2A histone family, member V
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
PBK PDZ binding kinase