BRD-K51276371_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K51276371_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AZU1 azurocidin 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCNA1 cyclin A1
ELANE elastase, neutrophil expressed
IGFBP7 insulin-like growth factor binding protein 7
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STC2 stanniocalcin 2
TPSAB1 tryptase alpha/beta 1
TXNIP thioredoxin interacting protein
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ANPEP alanyl (membrane) aminopeptidase
AQP3 aquaporin 3 (Gill blood group)
CDC25B cell division cycle 25B
CLIC4 chloride intracellular channel 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DMD dystrophin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
IFI44 interferon-induced protein 44
KDM5D lysine (K)-specific demethylase 5D
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
NEFH neurofilament, heavy polypeptide
PLAC8 placenta-specific 8
PPARG peroxisome proliferator-activated receptor gamma
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCTA T-cell leukemia translocation altered
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNC tenascin C
TUBB2A tubulin, beta 2A class IIa