BRD-K50866992_tropisetron hcl_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

29 genes differentially expressed following the BRD-K50866992_tropisetron hcl_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
AK4 adenylate kinase 4
CAST calpastatin
COL11A1 collagen, type XI, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
EFCAB14 EF-hand calcium binding domain 14
F5 coagulation factor V (proaccelerin, labile factor)
LDLR low density lipoprotein receptor
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MMP1 matrix metallopeptidase 1
PDGFC platelet derived growth factor C
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
THBS1 thrombospondin 1
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CCDC86 coiled-coil domain containing 86
CXCL13 chemokine (C-X-C motif) ligand 13
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FASTKD5 FAST kinase domains 5
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGKV1-5 immunoglobulin kappa variable 1-5
IGLV2-23 immunoglobulin lambda variable 2-23
MBP myelin basic protein
OLFM4 olfactomedin 4
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SRGN serglycin