BRD-K50387473_XMD-892_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K50387473_XMD-892_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APOC1 apolipoprotein C-I
C1S complement component 1, s subcomponent
C3 complement component 3
CCL20 chemokine (C-C motif) ligand 20
CCL5 chemokine (C-C motif) ligand 5
CLEC2B C-type lectin domain family 2, member B
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEPTOR DEP domain containing MTOR-interacting protein
DUSP1 dual specificity phosphatase 1
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENO2 enolase 2 (gamma, neuronal)
FAM69A family with sequence similarity 69, member A
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
IGF1 insulin-like growth factor 1 (somatomedin C)
KDM5D lysine (K)-specific demethylase 5D
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LRRC17 leucine rich repeat containing 17
NBL1 neuroblastoma 1, DAN family BMP antagonist
NKX3-1 NK3 homeobox 1
OLFM4 olfactomedin 4
PLXNC1 plexin C1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SCD5 stearoyl-CoA desaturase 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SNAI2 snail family zinc finger 2
STC1 stanniocalcin 1
TFPI2 tissue factor pathway inhibitor 2
TGFB3 transforming growth factor, beta 3
WFDC2 WAP four-disulfide core domain 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRELD2 cysteine-rich with EGF-like domains 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
ICAM2 intercellular adhesion molecule 2
IRS2 insulin receptor substrate 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLGN4X neuroligin 4, X-linked
NLRP2 NLR family, pyrin domain containing 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
PXDN peroxidasin
SDC4 syndecan 4
STAB1 stabilin 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDAC1 voltage-dependent anion channel 1
XIST X inactive specific transcript (non-protein coding)
ZBTB10 zinc finger and BTB domain containing 10