BRD-K50387473_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K50387473_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADCY9 adenylate cyclase 9
ANKRD10 ankyrin repeat domain 10
ASMTL acetylserotonin O-methyltransferase-like
ASPN asporin
CADM1 cell adhesion molecule 1
CALD1 caldesmon 1
CES1 carboxylesterase 1
CIRBP cold inducible RNA binding protein
COL11A1 collagen, type XI, alpha 1
CREG1 cellular repressor of E1A-stimulated genes 1
DUSP14 dual specificity phosphatase 14
EPAS1 endothelial PAS domain protein 1
FOLR1 folate receptor 1 (adult)
GADD45B growth arrest and DNA-damage-inducible, beta
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
JAG1 jagged 1
MSH6 mutS homolog 6
MYO1B myosin IB
NID2 nidogen 2 (osteonidogen)
PBX3 pre-B-cell leukemia homeobox 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
STMN2 stathmin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TUBB2A tubulin, beta 2A class IIa
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTN1 actinin, alpha 1
ANXA1 annexin A1
DENND2D DENN/MADD domain containing 2D
ESR1 estrogen receptor 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFRD2 interferon-related developmental regulator 2
JADE2 jade family PHD finger 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
MAGEA3 melanoma antigen family A3
MBNL2 muscleblind-like splicing regulator 2
MECOM MDS1 and EVI1 complex locus
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLBD1 phospholipase B domain containing 1
PPARG peroxisome proliferator-activated receptor gamma
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RGS2 regulator of G-protein signaling 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCERG1 transcription elongation regulator 1
TEX10 testis expressed 10
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN8 tetraspanin 8