BRD-K50311478_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K50311478_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANPEP alanyl (membrane) aminopeptidase
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP6 insulin-like growth factor binding protein 6
MCOLN1 mucolipin 1
MICALL1 MICAL-like 1
NQO1 NAD(P)H dehydrogenase, quinone 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CD24 CD24 molecule
CRISP3 cysteine-rich secretory protein 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
G0S2 G0/G1 switch 2
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
MAP7 microtubule-associated protein 7
MECOM MDS1 and EVI1 complex locus
PLN phospholamban
PRDX2 peroxiredoxin 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TKTL1 transketolase-like 1
TUBA4A tubulin, alpha 4a