BRD-K50204028_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K50204028_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL5 chemokine (C-C motif) ligand 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CP ceruloplasmin (ferroxidase)
CRABP2 cellular retinoic acid binding protein 2
EFS embryonal Fyn-associated substrate
FCGBP Fc fragment of IgG binding protein
FOLR1 folate receptor 1 (adult)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLUL glutamate-ammonia ligase
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
LUM lumican
LYZ lysozyme
MKNK1 MAP kinase interacting serine/threonine kinase 1
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
NCAM1 neural cell adhesion molecule 1
NDRG2 NDRG family member 2
PLBD1 phospholipase B domain containing 1
PLSCR3 phospholipid scramblase 3
QPCT glutaminyl-peptide cyclotransferase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RGS2 regulator of G-protein signaling 2
RTN1 reticulon 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNX10 sorting nexin 10
TBX3 T-box 3
TGFBR3 transforming growth factor, beta receptor III
TWF1 twinfilin actin binding protein 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLIC4 chloride intracellular channel 4
COG2 component of oligomeric golgi complex 2
CYFIP2 cytoplasmic FMR1 interacting protein 2
EFNB2 ephrin-B2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GRAMD3 GRAM domain containing 3
GSTM3 glutathione S-transferase mu 3 (brain)
H1F0 H1 histone family, member 0
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IGSF3 immunoglobulin superfamily, member 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ISOC1 isochorismatase domain containing 1
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
MET MET proto-oncogene, receptor tyrosine kinase
MYLK myosin light chain kinase
PMEPA1 prostate transmembrane protein, androgen induced 1
QKI QKI, KH domain containing, RNA binding
RGS5 regulator of G-protein signaling 5
RPL39L ribosomal protein L39-like
RPS5 ribosomal protein S5
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPTBN1 spectrin, beta, non-erythrocytic 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TJP2 tight junction protein 2
TLR4 toll-like receptor 4