BRD-K50168500_canertinib_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

75 genes differentially expressed following the BRD-K50168500_canertinib_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BID BH3 interacting domain death agonist
CAPN2 calpain 2, (m/II) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ETV5 ets variant 5
FRZB frizzled-related protein
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
NLGN4X neuroligin 4, X-linked
PLAC8 placenta-specific 8
PSAT1 phosphoserine aminotransferase 1
RNF144A ring finger protein 144A
SOCS2 suppressor of cytokine signaling 2
SPTBN1 spectrin, beta, non-erythrocytic 1
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPBG trophoblast glycoprotein
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CA12 carbonic anhydrase XII
CCL19 chemokine (C-C motif) ligand 19
CD24 CD24 molecule
CD52 CD52 molecule
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLTB clathrin, light chain B
CRCT1 cysteine-rich C-terminal 1
CRNN cornulin
CXCL13 chemokine (C-X-C motif) ligand 13
CYB5A cytochrome b5 type A (microsomal)
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFNB2 ephrin-B2
EMP1 epithelial membrane protein 1
F3 coagulation factor III (thromboplastin, tissue factor)
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
H1F0 H1 histone family, member 0
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INHBB inhibin, beta B
KRT4 keratin 4, type II
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP9 matrix metallopeptidase 9
PLAGL1 pleiomorphic adenoma gene-like 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RHCG Rh family, C glycoprotein
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
SIRT3 sirtuin 3
SPINK5 serine peptidase inhibitor, Kazal type 5
SPP1 secreted phosphoprotein 1
SPRR3 small proline-rich protein 3
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TMEM45A transmembrane protein 45A
TRAC T cell receptor alpha constant
TSC22D1 TSC22 domain family, member 1