BRD-K50168500_canertinib_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K50168500_canertinib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
HIST1H1C histone cluster 1, H1c
KDM3A lysine (K)-specific demethylase 3A
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
PTX3 pentraxin 3, long
SEPP1 selenoprotein P, plasma, 1
TFF1 trefoil factor 1
TTC39A tetratricopeptide repeat domain 39A

decreased expression

Symbol Name
AIM1 absent in melanoma 1
ARL4C ADP-ribosylation factor-like 4C
BTG2 BTG family, member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CTSH cathepsin H
DCN decorin
DEGS1 delta(4)-desaturase, sphingolipid 1
EGR1 early growth response 1
EGR2 early growth response 2
EZR ezrin
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
GATA3 GATA binding protein 3
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
JUNB jun B proto-oncogene
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHA5 pleckstrin homology domain containing, family A member 5
POSTN periostin, osteoblast specific factor
PTGDS prostaglandin D2 synthase 21kDa (brain)
RIN2 Ras and Rab interactor 2
TAGLN transgelin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZFP36L1 ZFP36 ring finger protein-like 1