BRD-K50140147_NVP-TAE684_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K50140147_NVP-TAE684_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
AQP1 aquaporin 1 (Colton blood group)
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CPA3 carboxypeptidase A3 (mast cell)
DSP desmoplakin
EFNB2 ephrin-B2
EZR ezrin
FGFR3 fibroblast growth factor receptor 3
GJA1 gap junction protein, alpha 1, 43kDa
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
LXN latexin
MAP7 microtubule-associated protein 7
MEF2C myocyte enhancer factor 2C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1M metallothionein 1M
NEFL neurofilament, light polypeptide
QPCT glutaminyl-peptide cyclotransferase
S100A8 S100 calcium binding protein A8
SDC2 syndecan 2
SFN stratifin
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPON1 spondin 1, extracellular matrix protein
TRAPPC4 trafficking protein particle complex 4
XIST X inactive specific transcript (non-protein coding)
ZNF586 zinc finger protein 586
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C14ORF132 chromosome 14 open reading frame 132
CCL5 chemokine (C-C motif) ligand 5
CLIC3 chloride intracellular channel 3
CTSC cathepsin C
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL6 chemokine (C-X-C motif) ligand 6
FXYD3 FXYD domain containing ion transport regulator 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HOMER3 homer scaffolding protein 3
HSPA2 heat shock 70kDa protein 2
IFI27 interferon, alpha-inducible protein 27
IL32 interleukin 32
IL6 interleukin 6
IRS2 insulin receptor substrate 2
KRT17 keratin 17, type I
KRT23 keratin 23, type I
MMP10 matrix metallopeptidase 10
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NEBL nebulette
PDZD2 PDZ domain containing 2
PSCA prostate stem cell antigen
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SORD sorbitol dehydrogenase