BRD-K50140147_NVP-TAE684_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K50140147_NVP-TAE684_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBR3 carbonyl reductase 3
CBS cystathionine-beta-synthase
CLDN10 claudin 10
CRYAB crystallin, alpha B
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM134B family with sequence similarity 134, member B
FGFR3 fibroblast growth factor receptor 3
HAPLN1 hyaluronan and proteoglycan link protein 1
HBB hemoglobin, beta
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOXB2 homeobox B2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MAL mal, T-cell differentiation protein
MTSS1 metastasis suppressor 1
MYH11 myosin, heavy chain 11, smooth muscle
PKD2 polycystic kidney disease 2 (autosomal dominant)
SATB1 SATB homeobox 1
SERINC5 serine incorporator 5
SPON1 spondin 1, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS1 tensin 1
TRIB2 tribbles pseudokinase 2
TUSC3 tumor suppressor candidate 3
VAV3 vav 3 guanine nucleotide exchange factor
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
C3ORF14 chromosome 3 open reading frame 14
CA2 carbonic anhydrase II
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIO2 deiodinase, iodothyronine, type II
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FABP4 fatty acid binding protein 4, adipocyte
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA3 GATA binding protein 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPRC5A G protein-coupled receptor, class C, group 5, member A
HK2 hexokinase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGL immunoglobulin lambda locus
KRT19 keratin 19, type I
LTF lactotransferrin
MAP7 microtubule-associated protein 7
ODC1 ornithine decarboxylase 1
PIP prolactin-induced protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RHOB ras homolog family member B
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLN sarcolipin
STC2 stanniocalcin 2
TOB1 transducer of ERBB2, 1
UBE2S ubiquitin-conjugating enzyme E2S
UGDH UDP-glucose 6-dehydrogenase
XIST X inactive specific transcript (non-protein coding)