BRD-K49865102_S1036_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

169 genes differentially expressed following the BRD-K49865102_S1036_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD4 abhydrolase domain containing 4
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
ACTA1 actin, alpha 1, skeletal muscle
ADA adenosine deaminase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BLCAP bladder cancer associated protein
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CELF2 CUGBP, Elav-like family member 2
CFD complement factor D (adipsin)
COL14A1 collagen, type XIV, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRYAB crystallin, alpha B
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPT dermatopontin
ELN elastin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM107A family with sequence similarity 107, member A
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GOLGA8A golgin A8 family, member A
GPM6B glycoprotein M6B
HBB hemoglobin, beta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
HTRA1 HtrA serine peptidase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RN interleukin 1 receptor antagonist
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KLF9 Kruppel-like factor 9
KLHL41 kelch-like family member 41
LIMCH1 LIM and calponin homology domains 1
MAPT microtubule-associated protein tau
MATN2 matrilin 2
MFAP4 microfibrillar-associated protein 4
MN1 meningioma (disrupted in balanced translocation) 1
MXRA5 matrix-remodelling associated 5
MYBPC1 myosin binding protein C, slow type
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEBL nebulette
NFIL3 nuclear factor, interleukin 3 regulated
NUPR1 nuclear protein, transcriptional regulator, 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHYH phytanoyl-CoA 2-hydroxylase
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
RYR1 ryanodine receptor 1 (skeletal)
S100A2 S100 calcium binding protein A2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLN sarcolipin
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SSBP2 single-stranded DNA binding protein 2
TACSTD2 tumor-associated calcium signal transducer 2
TES testin LIM domain protein
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM176A transmembrane protein 176A
TNNC1 troponin C type 1 (slow)
TNS3 tensin 3
TPD52L1 tumor protein D52-like 1
TSPAN8 tetraspanin 8
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF106 zinc finger protein 106

decreased expression

Symbol Name
BEX1 brain expressed, X-linked 1
CAPG capping protein (actin filament), gelsolin-like
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CD200 CD200 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
COG7 component of oligomeric golgi complex 7
COTL1 coactosin-like F-actin binding protein 1
CYBB cytochrome b-245, beta polypeptide
DESI2 desumoylating isopeptidase 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPN2 epsin 2
EREG epiregulin
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
FXYD5 FXYD domain containing ion transport regulator 5
GIMAP4 GTPase, IMAP family member 4
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HMGA2 high mobility group AT-hook 2
HPCAL1 hippocalcin-like 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV3-19 immunoglobulin lambda variable 3-19
KLF2 Kruppel-like factor 2
LDLR low density lipoprotein receptor
LPAR6 lysophosphatidic acid receptor 6
MAP2K3 mitogen-activated protein kinase kinase 3
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
PRTN3 proteinase 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS4 regulator of G-protein signaling 4
RRM2 ribonucleotide reductase M2
RTN1 reticulon 1
S100P S100 calcium binding protein P
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2B3 SH2B adaptor protein 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAP25 synaptosomal-associated protein, 25kDa
SPRY4 sprouty homolog 4 (Drosophila)
SQLE squalene epoxidase
SQRDL sulfide quinone reductase-like (yeast)
SRGN serglycin
STC1 stanniocalcin 1
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TRIB2 tribbles pseudokinase 2
VEGFC vascular endothelial growth factor C