BRD-K49865102_PD-0325901_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

168 genes differentially expressed following the BRD-K49865102_PD-0325901_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
ADAMDEC1 ADAM-like, decysin 1
ADCK3 aarF domain containing kinase 3
ADIRF adipogenesis regulatory factor
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHRDL1 chordin-like 1
CKM creatine kinase, muscle
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL5 chemokine (C-X-C motif) ligand 5
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM107A family with sequence similarity 107, member A
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
HSDL2 hydroxysteroid dehydrogenase like 2
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
IDO1 indoleamine 2,3-dioxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KCNK1 potassium channel, two pore domain subfamily K, member 1
KDM5D lysine (K)-specific demethylase 5D
KLF4 Kruppel-like factor 4 (gut)
KLHL41 kelch-like family member 41
KRT5 keratin 5, type II
LRRC17 leucine rich repeat containing 17
MAP7 microtubule-associated protein 7
MKNK2 MAP kinase interacting serine/threonine kinase 2
MUC2 mucin 2, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
MYBPC1 myosin binding protein C, slow type
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NRIP1 nuclear receptor interacting protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PLS1 plastin 1
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PTN pleiotrophin
RCAN2 regulator of calcineurin 2
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLN sarcolipin
SPINK1 serine peptidase inhibitor, Kazal type 1
SULF1 sulfatase 1
TMEM176B transmembrane protein 176B
TPM1 tropomyosin 1 (alpha)
TRIM29 tripartite motif containing 29
TTN titin
TWIST1 twist family bHLH transcription factor 1
VAV3 vav 3 guanine nucleotide exchange factor
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
AREG amphiregulin
BEX1 brain expressed, X-linked 1
CA2 carbonic anhydrase II
CCND1 cyclin D1
CD164 CD164 molecule, sialomucin
CDCP1 CUB domain containing protein 1
CHGB chromogranin B
CLDN1 claudin 1
CPE carboxypeptidase E
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
EREG epiregulin
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HBEGF heparin-binding EGF-like growth factor
HMGA2 high mobility group AT-hook 2
HPCAL1 hippocalcin-like 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT19 keratin 19, type I
LAMB3 laminin, beta 3
LDLR low density lipoprotein receptor
LIF leukemia inhibitory factor
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NELL2 NEL-like 2 (chicken)
NGRN neugrin, neurite outgrowth associated
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
ODC1 ornithine decarboxylase 1
OSMR oncostatin M receptor
PDE4B phosphodiesterase 4B, cAMP-specific
PEG10 paternally expressed 10
PEX11A peroxisomal biogenesis factor 11 alpha
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRNP prion protein
PROM1 prominin 1
RBP1 retinol binding protein 1, cellular
RELN reelin
RGCC regulator of cell cycle
RRM2 ribonucleotide reductase M2
S100A12 S100 calcium binding protein A12
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SHB Src homology 2 domain containing adaptor protein B
SLC35G2 solute carrier family 35, member G2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAP25 synaptosomal-associated protein, 25kDa
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SSBP2 single-stranded DNA binding protein 2
SSFA2 sperm specific antigen 2
STEAP3 STEAP family member 3, metalloreductase
STMN2 stathmin 2
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TBX2 T-box 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TM4SF1 transmembrane 4 L six family member 1
TRIB2 tribbles pseudokinase 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZFP36L1 ZFP36 ring finger protein-like 1