BRD-K49865102_PD-0325901_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K49865102_PD-0325901_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AHNAK2 AHNAK nucleoprotein 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CADM1 cell adhesion molecule 1
DMTF1 cyclin D binding myb-like transcription factor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGFR3 fibroblast growth factor receptor 3
GLDC glycine dehydrogenase (decarboxylating)
GPNMB glycoprotein (transmembrane) nmb
HMGB3 high mobility group box 3
IDE insulin-degrading enzyme
KLF4 Kruppel-like factor 4 (gut)
KLK11 kallikrein-related peptidase 11
KRT6A keratin 6A, type II
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LHX2 LIM homeobox 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
RAB21 RAB21, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
SCEL sciellin
SEPP1 selenoprotein P, plasma, 1
TCF4 transcription factor 4
TSPAN13 tetraspanin 13
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DSG2 desmoglein 2
FBP1 fructose-1,6-bisphosphatase 1
FOSL1 FOS-like antigen 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA3 GATA binding protein 3
IER3 immediate early response 3
KRT17 keratin 17, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBPF10 neuroblastoma breakpoint family, member 10
NR4A3 nuclear receptor subfamily 4, group A, member 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SRGN serglycin
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2