BRD-K49865102_PD-0325901_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

857 genes differentially expressed following the BRD-K49865102_PD-0325901_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ABAT 4-aminobutyrate aminotransferase
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD4 abhydrolase domain containing 4
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOC aldolase C, fructose-bisphosphate
AMOTL2 angiomotin like 2
ANGPTL2 angiopoietin-like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANO10 anoctamin 10
ANXA4 annexin A4
ANXA9 annexin A9
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMCX2 armadillo repeat containing, X-linked 2
ARMCX6 armadillo repeat containing, X-linked 6
ASPN asporin
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP10B ATPase, class V, type 10B
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP9A ATPase, class II, type 9A
BBS1 Bardet-Biedl syndrome 1
BCL6 B-cell CLL/lymphoma 6
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
C11ORF71 chromosome 11 open reading frame 71
C14ORF132 chromosome 14 open reading frame 132
C14ORF159 chromosome 14 open reading frame 159
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C3 complement component 3
C9ORF16 chromosome 9 open reading frame 16
C9ORF3 chromosome 9 open reading frame 3
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPN1 calpain 1, (mu/I) large subunit
CAPN3 calpain 3, (p94)
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC53 coiled-coil domain containing 53
CCDC92 coiled-coil domain containing 92
CCND2 cyclin D2
CCNG1 cyclin G1
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CD14 CD14 molecule
CD200 CD200 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CENPE centromere protein E, 312kDa
CFB complement factor B
CFD complement factor D (adipsin)
CFI complement factor I
CIRBP cold inducible RNA binding protein
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKB creatine kinase, brain
CLCN3 chloride channel, voltage-sensitive 3
CLIC3 chloride intracellular channel 3
CLIP3 CAP-GLY domain containing linker protein 3
CLU clusterin
CMC4 C-x(9)-C motif containing 4
CNN1 calponin 1, basic, smooth muscle
CNN3 calponin 3, acidic
COL14A1 collagen, type XIV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL21A1 collagen, type XXI, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A1 collagen, type V, alpha 1
COX5B cytochrome c oxidase subunit Vb
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CPQ carboxypeptidase Q
CRABP2 cellular retinoic acid binding protein 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRISP3 cysteine-rich secretory protein 3
CRYAB crystallin, alpha B
CSRP1 cysteine and glycine-rich protein 1
CTSH cathepsin H
CYBA cytochrome b-245, alpha polypeptide
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK1 death-associated protein kinase 1
DARS aspartyl-tRNA synthetase
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DCN decorin
DCT dopachrome tautomerase
DDB2 damage-specific DNA binding protein 2, 48kDa
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DES desmin
DHRS1 dehydrogenase/reductase (SDR family) member 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPYSL3 dihydropyrimidinase-like 3
DST dystonin
DUSP1 dual specificity phosphatase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
EPHA3 EPH receptor A3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
F13A1 coagulation factor XIII, A1 polypeptide
FADS1 fatty acid desaturase 1
FADS3 fatty acid desaturase 3
FAM134B family with sequence similarity 134, member B
FAM63A family with sequence similarity 63, member A
FBLN1 fibulin 1
FBLN5 fibulin 5
FDXR ferredoxin reductase
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
FOLR1 folate receptor 1 (adult)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FOXO4 forkhead box O4
FXYD3 FXYD domain containing ion transport regulator 3
GABARAP GABA(A) receptor-associated protein
GALC galactosylceramidase
GAS1 growth arrest-specific 1
GATA6 GATA binding protein 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
GOLPH3L golgi phosphoprotein 3-like
GPC4 glypican 4
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GPRC5B G protein-coupled receptor, class C, group 5, member B
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
GSTA4 glutathione S-transferase alpha 4
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GUSBP3 glucuronidase, beta pseudogene 3
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
H2BFS H2B histone family, member S (pseudogene)
HBP1 HMG-box transcription factor 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HLA-E major histocompatibility complex, class I, E
HMG20B high mobility group 20B
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGN3 high mobility group nucleosomal binding domain 3
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HOOK2 hook microtubule-tethering protein 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPG2 heparan sulfate proteoglycan 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDE insulin-degrading enzyme
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDUA iduronidase, alpha-L-
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL32 interleukin 32
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IRF9 interferon regulatory factor 9
ITGAV integrin, alpha V
ITGB4 integrin, beta 4
ITM2C integral membrane protein 2C
JUN jun proto-oncogene
JUND jun D proto-oncogene
JUP junction plakoglobin
KIAA1598
KLHL24 kelch-like family member 24
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT6A keratin 6A, type II
LAMB2 laminin, beta 2 (laminin S)
LAMP2 lysosomal-associated membrane protein 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCN2 lipocalin 2
LIMK2 LIM domain kinase 2
LMBRD1 LMBR1 domain containing 1
LOC100272216 uncharacterized LOC100272216
LTBP3 latent transforming growth factor beta binding protein 3
LXN latexin
LYPD1 LY6/PLAUR domain containing 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MAN2A1 mannosidase, alpha, class 2A, member 1
MAOB monoamine oxidase B
MAP1B microtubule-associated protein 1B
MAPT microtubule-associated protein tau
MATN2 matrilin 2
MDK midkine (neurite growth-promoting factor 2)
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MEF2C myocyte enhancer factor 2C
MEIS1 Meis homeobox 1
METRN meteorin, glial cell differentiation regulator
METTL7A methyltransferase like 7A
MMP11 matrix metallopeptidase 11
MN1 meningioma (disrupted in balanced translocation) 1
MSRB2 methionine sulfoxide reductase B2
MT1X metallothionein 1X
MTMR11 myotubularin related protein 11
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MVP major vault protein
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MXRA7 matrix-remodelling associated 7
MYLK myosin light chain kinase
MYO6 myosin VI
NBR1 neighbor of BRCA1 gene 1
NCAM1 neural cell adhesion molecule 1
NDRG2 NDRG family member 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NMRK1 nicotinamide riboside kinase 1
NNT nicotinamide nucleotide transhydrogenase
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NPC2 Niemann-Pick disease, type C2
NPEPL1 aminopeptidase-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRCAM neuronal cell adhesion molecule
NSG1 neuron specific gene family member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OLFM4 olfactomedin 4
OLFML2A olfactomedin-like 2A
OPTN optineurin
ORAI3 ORAI calcium release-activated calcium modulator 3
OSBPL9 oxysterol binding protein-like 9
OSR2 odd-skipped related transciption factor 2
PALLD palladin, cytoskeletal associated protein
PBX1 pre-B-cell leukemia homeobox 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDCD6 programmed cell death 6
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDLIM1 PDZ and LIM domain 1
PDLIM4 PDZ and LIM domain 4
PDZK1IP1 PDZK1 interacting protein 1
PDZRN3 PDZ domain containing ring finger 3
PEG3 paternally expressed 3
PFN2 profilin 2
PGAP3 post-GPI attachment to proteins 3
PHF21A PHD finger protein 21A
PHYH phytanoyl-CoA 2-hydroxylase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIR pirin (iron-binding nuclear protein)
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAGL1 pleiomorphic adenoma gene-like 1
PLCB4 phospholipase C, beta 4
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLP1 proteolipid protein 1
PLSCR3 phospholipid scramblase 3
PLXNB1 plexin B1
PNMA1 paraneoplastic Ma antigen 1
PNN pinin, desmosome associated protein
PNRC1 proline-rich nuclear receptor coactivator 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPAP2A phosphatidic acid phosphatase type 2A
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRAF2 PRA1 domain family, member 2
PRAME preferentially expressed antigen in melanoma
PRDX2 peroxiredoxin 2
PROS1 protein S (alpha)
PRSS23 protease, serine, 23
PRUNE2 prune homolog 2 (Drosophila)
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PYCARD PYD and CARD domain containing
PYGL phosphorylase, glycogen, liver
QPRT quinolinate phosphoribosyltransferase
RABAC1 Rab acceptor 1 (prenylated)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBP1 retinol binding protein 1, cellular
REEP1 receptor accessory protein 1
RGS1 regulator of G-protein signaling 1
RHOBTB3 Rho-related BTB domain containing 3
RHOQ ras homolog family member Q
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
ROGDI rogdi homolog (Drosophila)
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RPS27L ribosomal protein S27-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAD Ras-related associated with diabetes
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A4 S100 calcium binding protein A4
S100P S100 calcium binding protein P
SCAND1 SCAN domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCRG1 stimulator of chondrogenesis 1
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SECISBP2L SECIS binding protein 2-like
SELENBP1 selenium binding protein 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEPP1 selenoprotein P, plasma, 1
SEPW1 selenoprotein W, 1
SERF2 small EDRK-rich factor 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC22A18 solute carrier family 22, member 18
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35E2B solute carrier family 35, member E2B
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAI2 snail family zinc finger 2
SORBS1 sorbin and SH3 domain containing 1
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SPATA20 spermatogenesis associated 20
SPON2 spondin 2, extracellular matrix protein
SREBF1 sterol regulatory element binding transcription factor 1
SSBP2 single-stranded DNA binding protein 2
SSFA2 sperm specific antigen 2
SSPN sarcospan
SST somatostatin
ST5 suppression of tumorigenicity 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAP2 signal transducing adaptor family member 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SV2C synaptic vesicle glycoprotein 2C
SYNE2 spectrin repeat containing, nuclear envelope 2
SYT11 synaptotagmin XI
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAGLN transgelin
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCTA T-cell leukemia translocation altered
TDRD7 tudor domain containing 7
TGFBR3 transforming growth factor, beta receptor III
TGM1 transglutaminase 1
TM7SF2 transmembrane 7 superfamily member 2
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM134 transmembrane protein 134
TMEM135 transmembrane protein 135
TMEM35 transmembrane protein 35
TMEM47 transmembrane protein 47
TMEM59 transmembrane protein 59
TMOD1 tropomodulin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TNS1 tensin 1
TNS3 tensin 3
TOX thymocyte selection-associated high mobility group box
TPD52L1 tumor protein D52-like 1
TPGS2 tubulin polyglutamylase complex subunit 2
TPM2 tropomyosin 2 (beta)
TPP1 tripeptidyl peptidase I
TRAPPC6A trafficking protein particle complex 6A
TRIM2 tripartite motif containing 2
TRIM22 tripartite motif containing 22
TRIP6 thyroid hormone receptor interactor 6
TSPAN31 tetraspanin 31
TSPYL4 TSPY-like 4
TST thiosulfate sulfurtransferase (rhodanese)
TTC3 tetratricopeptide repeat domain 3
TTC39A tetratricopeptide repeat domain 39A
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
UBA7 ubiquitin-like modifier activating enzyme 7
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
VAT1 vesicle amine transport 1
VAV3 vav 3 guanine nucleotide exchange factor
VCL vinculin
VGLL4 vestigial-like family member 4
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WBP1L WW domain binding protein 1-like
WDR13 WD repeat domain 13
WDR45 WD repeat domain 45
WDTC1 WD and tetratricopeptide repeats 1
WFDC1 WAP four-disulfide core domain 1
WFDC2 WAP four-disulfide core domain 2
WIF1 WNT inhibitory factor 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WLS wntless Wnt ligand secretion mediator
WSB1 WD repeat and SOCS box containing 1
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1
ZMAT3 zinc finger, matrin-type 3
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRL2 adhesion G protein-coupled receptor L2
AK4 adenylate kinase 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMD1 adenosylmethionine decarboxylase 1
ANO1 anoctamin 1, calcium activated chloride channel
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA1 annexin A1
ANXA3 annexin A3
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
AURKA aurora kinase A
AURKB aurora kinase B
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2A1 BCL2-related protein A1
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BOP1 block of proliferation 1
BRCA1 breast cancer 1, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BZW1 basic leucine zipper and W2 domains 1
C6ORF62 chromosome 6 open reading frame 62
CA1 carbonic anhydrase I
CAB39 calcium binding protein 39
CBFB core-binding factor, beta subunit
CCDC86 coiled-coil domain containing 86
CCNA2 cyclin A2
CCND1 cyclin D1
CCND3 cyclin D3
CCNE2 cyclin E2
CCNF cyclin F
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3EAP CD3e molecule, epsilon associated protein
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDCA3 cell division cycle associated 3
CDCA4 cell division cycle associated 4
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CENPA centromere protein A
CENPN centromere protein N
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKS1B CDC28 protein kinase regulatory subunit 1B
COL13A1 collagen, type XIII, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COTL1 coactosin-like F-actin binding protein 1
CPVL carboxypeptidase, vitellogenic-like
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST1 cystatin SN
CST7 cystatin F (leukocystatin)
CSTA cystatin A (stefin A)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBF4 DBF4 zinc finger
DCLRE1C DNA cross-link repair 1C
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DEK DEK proto-oncogene
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMBP dynamin binding protein
DPT dermatopontin
DSCC1 DNA replication and sister chromatid cohesion 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ECT2 epithelial cell transforming 2
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EFHD2 EF-hand domain family, member D2
EGFR epidermal growth factor receptor
EGR3 early growth response 3
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5A eukaryotic translation initiation factor 5A
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO1 enolase 1, (alpha)
ENOPH1 enolase-phosphatase 1
EPHA2 EPH receptor A2
EREG epiregulin
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETV1 ets variant 1
ETV4 ets variant 4
ETV5 ets variant 5
EXO1 exonuclease 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM60A family with sequence similarity 60, member A
FANCI Fanconi anemia, complementation group I
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FEN1 flap structure-specific endonuclease 1
FGL2 fibrinogen-like 2
FKBP11 FK506 binding protein 11, 19 kDa
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAL galanin/GMAP prepropeptide
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCH1 GTP cyclohydrolase 1
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GINS3 GINS complex subunit 3 (Psf3 homolog)
GLS glutaminase
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRWD1 glutamate-rich WD repeat containing 1
GTPBP4 GTP binding protein 4
GTSE1 G-2 and S-phase expressed 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMK granzyme K (granzyme 3; tryptase II)
H2AFZ H2A histone family, member Z
HBEGF heparin-binding EGF-like growth factor
HELLS helicase, lymphoid-specific
HES1 hes family bHLH transcription factor 1
HIST1H2BG histone cluster 1, H2bg
HJURP Holliday junction recognition protein
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HOPX HOP homeobox
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA14 heat shock 70kDa protein 14
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IER3 immediate early response 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
IL2RG interleukin 2 receptor, gamma
IL7R interleukin 7 receptor
INHBA inhibin, beta A
ITGB5 integrin, beta 5
KCTD12 potassium channel tetramerization domain containing 12
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF23 kinesin family member 23
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LAMP5 lysosomal-associated membrane protein family, member 5
LEF1 lymphoid enhancer-binding factor 1
LMNB2 lamin B2
LPL lipoprotein lipase
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYZ lysozyme
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAK16 MAK16 homolog (S. cerevisiae)
MAP2K3 mitogen-activated protein kinase kinase 3
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MCUR1 mitochondrial calcium uniporter regulator 1
MELK maternal embryonic leucine zipper kinase
MGLL monoglyceride lipase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MICB MHC class I polypeptide-related sequence B
MKI67 marker of proliferation Ki-67
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MNDA myeloid cell nuclear differentiation antigen
MOK MOK protein kinase
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSH2 mutS homolog 2
MTCL1 microtubule crosslinking factor 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYBPC1 myosin binding protein C, slow type
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO10 myosin X
MYO1B myosin IB
NAE1 NEDD8 activating enzyme E1 subunit 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG non-SMC condensin I complex, subunit G
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NET1 neuroepithelial cell transforming 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFE2L3 nuclear factor, erythroid 2-like 3
NFIB nuclear factor I/B
NGRN neugrin, neurite outgrowth associated
NOL11 nucleolar protein 11
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP16 NOP16 nucleolar protein
NOP56 NOP56 ribonucleoprotein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
NUP62 nucleoporin 62kDa
NUP88 nucleoporin 88kDa
NUPL1 nucleoporin like 1
ODC1 ornithine decarboxylase 1
ORC1 origin recognition complex, subunit 1
ORC6 origin recognition complex, subunit 6
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PA2G4 proliferation-associated 2G4, 38kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAX5 paired box 5
PBK PDZ binding kinase
PCOLCE2 procollagen C-endopeptidase enhancer 2
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPAT phosphoribosyl pyrophosphate amidotransferase
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRC1 protein regulator of cytokinesis 1
PROSC proline synthetase co-transcribed homolog (bacterial)
PRPF4 pre-mRNA processing factor 4
PTGES3 prostaglandin E synthase 3 (cytosolic)
PUS7 pseudouridylate synthase 7 (putative)
RACGAP1 Rac GTPase activating protein 1
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD51C RAD51 paralog C
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RCC1 regulator of chromosome condensation 1
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFWD3 ring finger and WD repeat domain 3
RGS4 regulator of G-protein signaling 4
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCML1 sex comb on midleg-like 1 (Drosophila)
SDC2 syndecan 2
SEPHS1 selenophosphate synthetase 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
SH2B3 SH2B adaptor protein 3
SHCBP1 SHC SH2-domain binding protein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC43A3 solute carrier family 43, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMAGP small cell adhesion glycoprotein
SMC4 structural maintenance of chromosomes 4
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNX10 sorting nexin 10
SOX11 SRY (sex determining region Y)-box 11
SPC25 SPC25, NDC80 kinetochore complex component
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRM spermidine synthase
SRSF7 serine/arginine-rich splicing factor 7
STC1 stanniocalcin 1
STK17A serine/threonine kinase 17a
STX1A syntaxin 1A (brain)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACC2 transforming, acidic coiled-coil containing protein 2
TACC3 transforming, acidic coiled-coil containing protein 3
TACSTD2 tumor-associated calcium signal transducer 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TCL1A T-cell leukemia/lymphoma 1A
TESC tescalcin
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIPIN TIMELESS interacting protein
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM2 transmembrane protein 2
TMEM204 transmembrane protein 204
TMEM70 transmembrane protein 70
TMEM97 transmembrane protein 97
TMPO thymopoietin
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOP2A topoisomerase (DNA) II alpha 170kDa
TPM4 tropomyosin 4
TPX2 TPX2, microtubule-associated
TRAC T cell receptor alpha constant
TRIP13 thyroid hormone receptor interactor 13
TSPAN5 tetraspanin 5
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBG1 tubulin, gamma 1
TYMS thymidylate synthetase
TYRP1 tyrosinase-related protein 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UCK2 uridine-cytidine kinase 2
UGCG UDP-glucose ceramide glucosyltransferase
UPP1 uridine phosphorylase 1
USP1 ubiquitin specific peptidase 1
VRK1 vaccinia related kinase 1
WSB2 WD repeat and SOCS box containing 2
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZMYM2 zinc finger, MYM-type 2
ZNF331 zinc finger protein 331
ZWINT ZW10 interacting kinetochore protein