BRD-K49814456_2-{3-nitroanilino}-N-({5-nitro-2-furyl}methylene)acetohydrazide BRD-K73819439_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K49814456_2-{3-nitroanilino}-N-({5-nitro-2-furyl}methylene)acetohydrazide BRD-K73819439_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AGR2 anterior gradient 2
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
BIK BCL2-interacting killer (apoptosis-inducing)
CDC42 cell division cycle 42
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHPT1 choline phosphotransferase 1
CLDN18 claudin 18
CLIC3 chloride intracellular channel 3
COG2 component of oligomeric golgi complex 2
CPVL carboxypeptidase, vitellogenic-like
CRIP1 cysteine-rich protein 1 (intestinal)
CST3 cystatin C
CSTA cystatin A (stefin A)
CTSB cathepsin B
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EMP3 epithelial membrane protein 3
FOLR1 folate receptor 1 (adult)
GMDS GDP-mannose 4,6-dehydratase
IL1RN interleukin 1 receptor antagonist
KLF2 Kruppel-like factor 2
KRT4 keratin 4, type II
MBNL2 muscleblind-like splicing regulator 2
MTA1 metastasis associated 1
NAV3 neuron navigator 3
NKX3-1 NK3 homeobox 1
NPR3 natriuretic peptide receptor 3
PKM pyruvate kinase, muscle
PKN2 protein kinase N2
PLAC8 placenta-specific 8
PLEC plectin
RBKS ribokinase
S100A11 S100 calcium binding protein A11
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SPRR3 small proline-rich protein 3
SRSF6 serine/arginine-rich splicing factor 6
SVIL supervillin
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNPO1 transportin 1
TRIM16 tripartite motif containing 16
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ARMCX2 armadillo repeat containing, X-linked 2
C3ORF14 chromosome 3 open reading frame 14
CCND2 cyclin D2
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
CTGF connective tissue growth factor
CXCL13 chemokine (C-X-C motif) ligand 13
DCN decorin
DEPTOR DEP domain containing MTOR-interacting protein
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPP4 dipeptidyl-peptidase 4
DPYSL3 dihydropyrimidinase-like 3
EGFL6 EGF-like-domain, multiple 6
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
FHOD3 formin homology 2 domain containing 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBB hemoglobin, beta
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
INHBB inhibin, beta B
LPAR6 lysophosphatidic acid receptor 6
LUM lumican
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MECOM MDS1 and EVI1 complex locus
MFAP5 microfibrillar associated protein 5
NCAM1 neural cell adhesion molecule 1
ORM1 orosomucoid 1
PAPD7 PAP associated domain containing 7
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POU2AF1 POU class 2 associating factor 1
PTGIS prostaglandin I2 (prostacyclin) synthase
QPCT glutaminyl-peptide cyclotransferase
RAB21 RAB21, member RAS oncogene family
RAD51AP1 RAD51 associated protein 1
RFTN1 raftlin, lipid raft linker 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN1 reticulon 1
SDC1 syndecan 1
SEPT10 septin 10
SNX7 sorting nexin 7
SPON1 spondin 1, extracellular matrix protein
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
VAMP8 vesicle-associated membrane protein 8
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2
ZNF331 zinc finger protein 331