BRD-K49448285_Bisindolylmaleimide IV_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K49448285_Bisindolylmaleimide IV_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP1 aquaporin 1 (Colton blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CD52 CD52 molecule
CD9 CD9 molecule
CD93 CD93 molecule
CPA3 carboxypeptidase A3 (mast cell)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FHL1 four and a half LIM domains 1
IFI44 interferon-induced protein 44
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
KCTD12 potassium channel tetramerization domain containing 12
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LIMCH1 LIM and calponin homology domains 1
MFAP2 microfibrillar-associated protein 2
MYO6 myosin VI
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX1 pre-B-cell leukemia homeobox 1
PTPRK protein tyrosine phosphatase, receptor type, K
S100A8 S100 calcium binding protein A8
TYMP thymidine phosphorylase
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CASP7 caspase 7, apoptosis-related cysteine peptidase
CD99 CD99 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DSG1 desmoglein 1
EFNB2 ephrin-B2
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
EPHA3 EPH receptor A3
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM162A family with sequence similarity 162, member A
FLG filaggrin
GPI glucose-6-phosphate isomerase
HK2 hexokinase 2
HOXC6 homeobox C6
MACF1 microtubule-actin crosslinking factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
OLFM4 olfactomedin 4
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKL phosphofructokinase, liver
PGK1 phosphoglycerate kinase 1
PTX3 pentraxin 3, long
RNASET2 ribonuclease T2
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPAG4 sperm associated antigen 4
SST somatostatin
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TMEM176B transmembrane protein 176B