BRD-K49328571_dasatinib_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K49328571_dasatinib_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAMDEC1 ADAM-like, decysin 1
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANPEP alanyl (membrane) aminopeptidase
AVPI1 arginine vasopressin-induced 1
BASP1 brain abundant, membrane attached signal protein 1
BCL3 B-cell CLL/lymphoma 3
BIRC3 baculoviral IAP repeat containing 3
C8ORF4 chromosome 8 open reading frame 4
CCL5 chemokine (C-C motif) ligand 5
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL6A2 collagen, type VI, alpha 2
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
FAS Fas cell surface death receptor
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HOXA5 homeobox A5
ITM2C integral membrane protein 2C
LTBP3 latent transforming growth factor beta binding protein 3
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
PBX1 pre-B-cell leukemia homeobox 1
PTGES prostaglandin E synthase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
SATB1 SATB homeobox 1
SLC38A1 solute carrier family 38, member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SOD2 superoxide dismutase 2, mitochondrial
SPRED2 sprouty-related, EVH1 domain containing 2
SRPX sushi-repeat containing protein, X-linked
STC1 stanniocalcin 1
STK39 serine threonine kinase 39
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSC22D3 TSC22 domain family, member 3
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALOX5 arachidonate 5-lipoxygenase
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CADM1 cell adhesion molecule 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EDN1 endothelin 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOSL1 FOS-like antigen 1
FST follistatin
GADD45B growth arrest and DNA-damage-inducible, beta
HIST1H2BG histone cluster 1, H2bg
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
LCN2 lipocalin 2
MNDA myeloid cell nuclear differentiation antigen
MYC v-myc avian myelocytomatosis viral oncogene homolog
RHOB ras homolog family member B
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC1 syndecan 1
SFRP4 secreted frizzled-related protein 4
SHOX2 short stature homeobox 2
TACSTD2 tumor-associated calcium signal transducer 2
TBX2 T-box 2
THBS1 thrombospondin 1
TXNDC9 thioredoxin domain containing 9