BRD-K49328571_dasatinib_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K49328571_dasatinib_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AQP3 aquaporin 3 (Gill blood group)
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
CFD complement factor D (adipsin)
CHRDL1 chordin-like 1
CLU clusterin
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DDIT4 DNA-damage-inducible transcript 4
ETV1 ets variant 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPM6B glycoprotein M6B
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
IL2RB interleukin 2 receptor, beta
KRT13 keratin 13, type I
LTF lactotransferrin
NRGN neurogranin (protein kinase C substrate, RC3)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAB31 RAB31, member RAS oncogene family
RHOBTB3 Rho-related BTB domain containing 3
RUNX3 runt-related transcription factor 3
SCGB1D2 secretoglobin, family 1D, member 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
TRIP6 thyroid hormone receptor interactor 6
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA3 annexin A3
ARHGAP29 Rho GTPase activating protein 29
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP10B ATPase, class V, type 10B
AUTS2 autism susceptibility candidate 2
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD24 CD24 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL3A1 collagen, type III, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTGF connective tissue growth factor
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLC1 DLC1 Rho GTPase activating protein
EDN1 endothelin 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHA2 EPH receptor A2
FILIP1L filamin A interacting protein 1-like
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
HEPH hephaestin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IER3 immediate early response 3
INSIG1 insulin induced gene 1
KIAA1033 KIAA1033
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
MATN2 matrilin 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCDH9 protocadherin 9
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PODXL podocalyxin-like
PTX3 pentraxin 3, long
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT3 sirtuin 3
SPP1 secreted phosphoprotein 1
SQLE squalene epoxidase
STK26 serine/threonine protein kinase 26
SULF1 sulfatase 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN transgelin
TARDBP TAR DNA binding protein
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TMEM47 transmembrane protein 47
TMOD1 tropomodulin 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8