BRD-K49328571_dasatinib_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K49328571_dasatinib_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CDC25B cell division cycle 25B
DDIT4 DNA-damage-inducible transcript 4
FBLN1 fibulin 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITM2A integral membrane protein 2A
KRT14 keratin 14, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MGLL monoglyceride lipase
MTSS1 metastasis suppressor 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
RBPMS RNA binding protein with multiple splicing
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SFN stratifin
SLAMF1 signaling lymphocytic activation molecule family member 1
TFPI2 tissue factor pathway inhibitor 2
THYN1 thymocyte nuclear protein 1
TUBB6 tubulin, beta 6 class V

decreased expression

Symbol Name
C5AR1 complement component 5a receptor 1
CCL2 chemokine (C-C motif) ligand 2
CD14 CD14 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DUSP10 dual specificity phosphatase 10
EDN1 endothelin 1
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ESRP1 epithelial splicing regulatory protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLNB filamin B, beta
FOSL1 FOS-like antigen 1
FOXG1 forkhead box G1
FPR1 formyl peptide receptor 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
HBB hemoglobin, beta
IER3 immediate early response 3
KCTD12 potassium channel tetramerization domain containing 12
KLF10 Kruppel-like factor 10
KLF5 Kruppel-like factor 5 (intestinal)
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MNDA myeloid cell nuclear differentiation antigen
MYBPC1 myosin binding protein C, slow type
NAMPT nicotinamide phosphoribosyltransferase
NEBL nebulette
NPY1R neuropeptide Y receptor Y1
NRN1 neuritin 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PROM1 prominin 1
RAD23B RAD23 homolog B (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SON SON DNA binding protein
SOX9 SRY (sex determining region Y)-box 9
VCAN versican
ZBTB18 zinc finger and BTB domain containing 18