BRD-K49328571_dasatinib_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K49328571_dasatinib_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADD3 adducin 3 (gamma)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AQP3 aquaporin 3 (Gill blood group)
BAMBI BMP and activin membrane-bound inhibitor
CA12 carbonic anhydrase XII
CD44 CD44 molecule (Indian blood group)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFD complement factor D (adipsin)
CLU clusterin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F13A1 coagulation factor XIII, A1 polypeptide
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FXYD3 FXYD domain containing ion transport regulator 3
IGL immunoglobulin lambda locus
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LXN latexin
MUC5B mucin 5B, oligomeric mucus/gel-forming
NTS neurotensin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PROS1 protein S (alpha)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLPI secretory leukocyte peptidase inhibitor
TMEM47 transmembrane protein 47
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ANXA3 annexin A3
CCL2 chemokine (C-C motif) ligand 2
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A1 collagen, type V, alpha 1
CYR61 cysteine-rich, angiogenic inducer, 61
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GLIPR1 GLI pathogenesis-related 1
INHBA inhibin, beta A
LGALS1 lectin, galactoside-binding, soluble, 1
LTF lactotransferrin
NGRN neugrin, neurite outgrowth associated
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRPF4 pre-mRNA processing factor 4
PSPH phosphoserine phosphatase
RAD23B RAD23 homolog B (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SQLE squalene epoxidase
THBS1 thrombospondin 1
TPM1 tropomyosin 1 (alpha)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1