BRD-K49183052_VU0415113-1_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K49183052_VU0415113-1_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP4 bone morphogenetic protein 4
C10ORF10 chromosome 10 open reading frame 10
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CXCL10 chemokine (C-X-C motif) ligand 10
DPYSL3 dihydropyrimidinase-like 3
EPAS1 endothelial PAS domain protein 1
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
LAMP3 lysosomal-associated membrane protein 3
LGALS4 lectin, galactoside-binding, soluble, 4
LRMP lymphoid-restricted membrane protein
MAN1A1 mannosidase, alpha, class 1A, member 1
MME membrane metallo-endopeptidase
PBX3 pre-B-cell leukemia homeobox 3
PPP1R16B protein phosphatase 1, regulatory subunit 16B
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SFTPC surfactant protein C
SHB Src homology 2 domain containing adaptor protein B
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX7 sorting nexin 7
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TCF4 transcription factor 4
TM9SF3 transmembrane 9 superfamily member 3
TMEM30B transmembrane protein 30B
TMPRSS3 transmembrane protease, serine 3
UBE2J1 ubiquitin-conjugating enzyme E2, J1

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD10 ankyrin repeat domain 10
BASP1 brain abundant, membrane attached signal protein 1
CRISP3 cysteine-rich secretory protein 3
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FAT1 FAT atypical cadherin 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
IFITM3 interferon induced transmembrane protein 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
ODC1 ornithine decarboxylase 1
PIH1D1 PIH1 domain containing 1
STAMBP STAM binding protein
TCTA T-cell leukemia translocation altered
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNC tenascin C
TSPYL5 TSPY-like 5