BRD-K49094915_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K49094915_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLNS1A chloride channel, nucleotide-sensitive, 1A
CXADR coxsackie virus and adenovirus receptor
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ENO2 enolase 2 (gamma, neuronal)
ERP29 endoplasmic reticulum protein 29
FAM129A family with sequence similarity 129, member A
FAM57A family with sequence similarity 57, member A
HK2 hexokinase 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KCTD14 potassium channel tetramerization domain containing 14
KDM3A lysine (K)-specific demethylase 3A
LEF1 lymphoid enhancer-binding factor 1
LGALS8 lectin, galactoside-binding, soluble, 8
LY96 lymphocyte antigen 96
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MMP12 matrix metallopeptidase 12
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NDRG1 N-myc downstream regulated 1
NEFH neurofilament, heavy polypeptide
NTS neurotensin
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PEA15 phosphoprotein enriched in astrocytes 15
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
RALGDS ral guanine nucleotide dissociation stimulator
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPON1 spondin 1, extracellular matrix protein
STC2 stanniocalcin 2
TBX3 T-box 3
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TOX3 TOX high mobility group box family member 3
VEGFA vascular endothelial growth factor A
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
AZU1 azurocidin 1
CCL19 chemokine (C-C motif) ligand 19
CRISP3 cysteine-rich secretory protein 3
CST7 cystatin F (leukocystatin)
CTSG cathepsin G
CXCL12 chemokine (C-X-C motif) ligand 12
DCXR dicarbonyl/L-xylulose reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
ELANE elastase, neutrophil expressed
HSPB8 heat shock 22kDa protein 8
KIF14 kinesin family member 14
LGALS1 lectin, galactoside-binding, soluble, 1
LPAR1 lysophosphatidic acid receptor 1
LTF lactotransferrin
PCOLCE procollagen C-endopeptidase enhancer
PDGFRL platelet-derived growth factor receptor-like
PSENEN presenilin enhancer gamma secretase subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
RELN reelin
RPS11 ribosomal protein S11
TARP TCR gamma alternate reading frame protein
TBCB tubulin folding cofactor B
THBS1 thrombospondin 1
TSPYL5 TSPY-like 5
VNN1 vanin 1