BRD-K49094915_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K49094915_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
GLRX glutaredoxin (thioltransferase)
IGFBP3 insulin-like growth factor binding protein 3
KDM3A lysine (K)-specific demethylase 3A
LPAR1 lysophosphatidic acid receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1M metallothionein 1M
NAMPT nicotinamide phosphoribosyltransferase
NDRG1 N-myc downstream regulated 1
NFIL3 nuclear factor, interleukin 3 regulated
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PKM pyruvate kinase, muscle
RGS2 regulator of G-protein signaling 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC38A2 solute carrier family 38, member 2
SOD2 superoxide dismutase 2, mitochondrial
SPRED2 sprouty-related, EVH1 domain containing 2
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
CCNF cyclin F
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
MEIS2 Meis homeobox 2
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
RBP1 retinol binding protein 1, cellular
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SMAD1 SMAD family member 1
ZFPM2 zinc finger protein, FOG family member 2