BRD-K49061529_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K49061529_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD99 CD99 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
HIST1H1C histone cluster 1, H1c
ITM2C integral membrane protein 2C
LPAR6 lysophosphatidic acid receptor 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP12 matrix metallopeptidase 12
P3H2 prolyl 3-hydroxylase 2
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
SLC38A2 solute carrier family 38, member 2
SPON2 spondin 2, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
AGR2 anterior gradient 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOD apolipoprotein D
BST2 bone marrow stromal cell antigen 2
CALU calumenin
CCND1 cyclin D1
CD24 CD24 molecule
CDC42 cell division cycle 42
CLIC4 chloride intracellular channel 4
CRYAB crystallin, alpha B
EIF5A eukaryotic translation initiation factor 5A
EVL Enah/Vasp-like
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL13RA2 interleukin 13 receptor, alpha 2
LPL lipoprotein lipase
NFIB nuclear factor I/B
PBX1 pre-B-cell leukemia homeobox 1
QDPR quinoid dihydropteridine reductase
RBM47 RNA binding motif protein 47
RPS11 ribosomal protein S11
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SPATS2L spermatogenesis associated, serine-rich 2-like
SRPX sushi-repeat containing protein, X-linked
TSPAN13 tetraspanin 13
ZBTB38 zinc finger and BTB domain containing 38