BRD-K49061529_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K49061529_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY9 adenylate cyclase 9
ARMCX2 armadillo repeat containing, X-linked 2
CA11 carbonic anhydrase XI
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHN2 chimerin 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CKM creatine kinase, muscle
CRABP2 cellular retinoic acid binding protein 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTBP2 C-terminal binding protein 2
CYBRD1 cytochrome b reductase 1
CYTIP cytohesin 1 interacting protein
DRAM1 DNA-damage regulated autophagy modulator 1
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FGFR2 fibroblast growth factor receptor 2
FTH1 ferritin, heavy polypeptide 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIST1H1C histone cluster 1, H1c
HMGB2 high mobility group box 2
HYOU1 hypoxia up-regulated 1
JCHAIN joining chain of multimeric IgA and IgM
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
MB myoglobin
MMP2 matrix metallopeptidase 2
MN1 meningioma (disrupted in balanced translocation) 1
MYBPC1 myosin binding protein C, slow type
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NEB nebulin
NEFH neurofilament, heavy polypeptide
NFE2L2 nuclear factor, erythroid 2-like 2
NPTX2 neuronal pentraxin II
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRL platelet-derived growth factor receptor-like
PFKM phosphofructokinase, muscle
PLK2 polo-like kinase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SCUBE2 signal peptide, CUB domain, EGF-like 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOD2 superoxide dismutase 2, mitochondrial
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNNC2 troponin C type 2 (fast)
TNNT1 troponin T type 1 (skeletal, slow)
TPD52L1 tumor protein D52-like 1
TPM2 tropomyosin 2 (beta)
TTN titin
TUBA1A tubulin, alpha 1a
ZNF217 zinc finger protein 217
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
APOA2 apolipoprotein A-II
APOE apolipoprotein E
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
C8ORF4 chromosome 8 open reading frame 4
CD24 CD24 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GPC3 glypican 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
NEBL nebulette
PCDH9 protocadherin 9
PEBP1 phosphatidylethanolamine binding protein 1
PITX1 paired-like homeodomain 1
RBP4 retinol binding protein 4, plasma
RNF167 ring finger protein 167
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100B S100 calcium binding protein B
S100P S100 calcium binding protein P
SORD sorbitol dehydrogenase
STOM stomatin
STX1A syntaxin 1A (brain)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
ZMIZ1 zinc finger, MIZ-type containing 1