BRD-K49055432_A66_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K49055432_A66_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
BANK1 B-cell scaffold protein with ankyrin repeats 1
BTG1 B-cell translocation gene 1, anti-proliferative
CDK6 cyclin-dependent kinase 6
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CRELD2 cysteine-rich with EGF-like domains 2
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
GDF15 growth differentiation factor 15
GPRC5A G protein-coupled receptor, class C, group 5, member A
GREM1 gremlin 1, DAN family BMP antagonist
IGKC immunoglobulin kappa constant
KDM5D lysine (K)-specific demethylase 5D
KRT23 keratin 23, type I
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
METTL7A methyltransferase like 7A
MGLL monoglyceride lipase
MMP7 matrix metallopeptidase 7
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NRIP1 nuclear receptor interacting protein 1
OAT ornithine aminotransferase
PLAT plasminogen activator, tissue
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RABGAP1L RAB GTPase activating protein 1-like
RHOBTB3 Rho-related BTB domain containing 3
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SC5D sterol-C5-desaturase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SRPX sushi-repeat containing protein, X-linked
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGFA transforming growth factor, alpha
TPR translocated promoter region, nuclear basket protein
TSPAN3 tetraspanin 3
UGCG UDP-glucose ceramide glucosyltransferase
WFDC2 WAP four-disulfide core domain 2
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
BZW2 basic leucine zipper and W2 domains 2
CD93 CD93 molecule
CLEC11A C-type lectin domain family 11, member A
CRIP2 cysteine-rich protein 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYCS cytochrome c, somatic
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GGCT gamma-glutamylcyclotransferase
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL13RA2 interleukin 13 receptor, alpha 2
ITGAV integrin, alpha V
ITM2A integral membrane protein 2A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LPAR6 lysophosphatidic acid receptor 6
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MCAM melanoma cell adhesion molecule
METRN meteorin, glial cell differentiation regulator
MT1X metallothionein 1X
PEG3 paternally expressed 3
PLK1 polo-like kinase 1
PLS3 plastin 3
POLD2 polymerase (DNA directed), delta 2, accessory subunit
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RGCC regulator of cell cycle
S100A10 S100 calcium binding protein A10
SDC2 syndecan 2
SEC61G Sec61 gamma subunit
TCTN1 tectonic family member 1
UPP1 uridine phosphorylase 1
XIST X inactive specific transcript (non-protein coding)