BRD-K48803730_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K48803730_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADA adenosine deaminase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANXA1 annexin A1
APP amyloid beta (A4) precursor protein
ARID5B AT rich interactive domain 5B (MRF1-like)
C10ORF10 chromosome 10 open reading frame 10
CALB2 calbindin 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
CTSZ cathepsin Z
DUSP6 dual specificity phosphatase 6
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FADS1 fatty acid desaturase 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
IL1B interleukin 1, beta
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
LGALS1 lectin, galactoside-binding, soluble, 1
MLPH melanophilin
MMP7 matrix metallopeptidase 7
PCOLCE2 procollagen C-endopeptidase enhancer 2
PMP22 peripheral myelin protein 22
RAB27A RAB27A, member RAS oncogene family
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOX9 SRY (sex determining region Y)-box 9
SRSF5 serine/arginine-rich splicing factor 5
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF3IP2 TRAF3 interacting protein 2
TSC22D1 TSC22 domain family, member 1
VCAN versican

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND2 cyclin D2
CXCL13 chemokine (C-X-C motif) ligand 13
FBXO21 F-box protein 21
H2AFX H2A histone family, member X
IGFBP7 insulin-like growth factor binding protein 7
JMJD6 jumonji domain containing 6
PDZD8 PDZ domain containing 8
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PTS 6-pyruvoyltetrahydropterin synthase
TMPO thymopoietin
VCP valosin containing protein
ZW10 zw10 kinetochore protein