BRD-K48803730_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K48803730_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADIRF adipogenesis regulatory factor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
ARG2 arginase 2
CADM1 cell adhesion molecule 1
CCDC85B coiled-coil domain containing 85B
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COMP cartilage oligomeric matrix protein
CRABP2 cellular retinoic acid binding protein 2
CSRP1 cysteine and glycine-rich protein 1
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DDAH1 dimethylarginine dimethylaminohydrolase 1
DUSP10 dual specificity phosphatase 10
EIF5A eukaryotic translation initiation factor 5A
GJA1 gap junction protein, alpha 1, 43kDa
HBB hemoglobin, beta
HYAL1 hyaluronoglucosaminidase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
ITGA6 integrin, alpha 6
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LYZ lysozyme
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MARCKSL1 MARCKS-like 1
MMP11 matrix metallopeptidase 11
NIT1 nitrilase 1
NPTX2 neuronal pentraxin II
NR2F1 nuclear receptor subfamily 2, group F, member 1
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PKP2 plakophilin 2
PLS1 plastin 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TMSB15A thymosin beta 15a
TPD52 tumor protein D52
TPD52L1 tumor protein D52-like 1
WASF1 WAS protein family, member 1
XIST X inactive specific transcript (non-protein coding)
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
CDC25A cell division cycle 25A
CELF2 CUGBP, Elav-like family member 2
CHL1 cell adhesion molecule L1-like
CREB1 cAMP responsive element binding protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKC1 dyskeratosis congenita 1, dyskerin
FAM57A family with sequence similarity 57, member A
HMGA2 high mobility group AT-hook 2
IFITM1 interferon induced transmembrane protein 1
KDM5D lysine (K)-specific demethylase 5D
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP1 secreted frizzled-related protein 1
TLK2 tousled-like kinase 2
TNPO1 transportin 1