BRD-K48654774_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K48654774_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BBX bobby sox homolog (Drosophila)
BIK BCL2-interacting killer (apoptosis-inducing)
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CCNA1 cyclin A1
CCNG2 cyclin G2
CD47 CD47 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLCN4 chloride channel, voltage-sensitive 4
CLEC2B C-type lectin domain family 2, member B
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP22 dual specificity phosphatase 22
EVI2A ecotropic viral integration site 2A
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO4 forkhead box O4
FSTL1 follistatin-like 1
GLRX glutaredoxin (thioltransferase)
GPM6A glycoprotein M6A
GULP1 GULP, engulfment adaptor PTB domain containing 1
HSPA1A heat shock 70kDa protein 1A
IFITM1 interferon induced transmembrane protein 1
IL32 interleukin 32
L1CAM L1 cell adhesion molecule
LCK LCK proto-oncogene, Src family tyrosine kinase
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MMD monocyte to macrophage differentiation-associated
NAMPT nicotinamide phosphoribosyltransferase
OLFM4 olfactomedin 4
PAM peptidylglycine alpha-amidating monooxygenase
PNMA2 paraneoplastic Ma antigen 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROM1 prominin 1
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
REEP1 receptor accessory protein 1
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SDCBP syndecan binding protein (syntenin)
SEPP1 selenoprotein P, plasma, 1
SKAP2 src kinase associated phosphoprotein 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
STOM stomatin
TAC1 tachykinin, precursor 1
TFPI2 tissue factor pathway inhibitor 2
TMSB15A thymosin beta 15a
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRAK2 trafficking protein, kinesin binding 2
TRIL TLR4 interactor with leucine-rich repeats
TXNDC9 thioredoxin domain containing 9
TXNIP thioredoxin interacting protein
VCAM1 vascular cell adhesion molecule 1
WWC3 WWC family member 3
ZIC1 Zic family member 1

decreased expression

Symbol Name
ATF5 activating transcription factor 5
C4BPA complement component 4 binding protein, alpha
CADM1 cell adhesion molecule 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD93 CD93 molecule
CDCA4 cell division cycle associated 4
CDKN2A cyclin-dependent kinase inhibitor 2A
DNM1L dynamin 1-like
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXOSC4 exosome component 4
FAM57A family with sequence similarity 57, member A
FGB fibrinogen beta chain
FPGS folylpolyglutamate synthase
GABPB1 GA binding protein transcription factor, beta subunit 1
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2BG histone cluster 1, H2bg
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LTF lactotransferrin
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP12 matrix metallopeptidase 12
POSTN periostin, osteoblast specific factor
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
THBS1 thrombospondin 1